Animal Mouse Physiology Core – Serving Vanderbilt Investigators
Instruments and Equipment
We have several instruments and equipment for self-use:
- Promethion - Body composition
- Metabolic cage rental
- Pair-feeding hoppers
- Temperature regulated housing cabinet
- Telemetry System
- SomnoSuite
- Oroboros O2K
Courses & Education
- Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis (November 7-11, 2022)
- Glucose Clamping the Conscious Mouse: A Laboratory Course Mouse Metabolic Phenotyping Center - Vanderbilt University Nashville, TN (October 17-21, 2022)
- See JoVE Production on the Vanderbilt Clamp
- MMPC Grant Programs
Our Mission
To advance research by providing novel experimental tools to the scientific community for phenotyping genetic mouse models related to diabetes, obesity, and other metabolic diseases.Our Goals
- Broaden the scope of techniques available to investigators
- Standardize key methodologies
- Expedite the completion of research
- Compile a database for mouse models of diabetes
Twitter Feed
This should help with definitions and characterization of mouse models. https://t.co/hfFqhy53Go
Excited to have @sarah_stern of Max Planck Florida Institute for Neuroscience speak at Vanderbilt. Great stuff. Electric! @VCARScience @VUBasicSciences https://t.co/AmCIP7aoqW
Fascinating study suggests that when a subject loses weight they need to commit to keeping it off. Repercussions of weight regain are bad for health. https://t.co/XWKzSnizuK
On this Veteran's Day the VMMPC expresses its appreciation and admiration for all those who served our country. #RESPECT
Recent Publications
- The endothelial-enriched lncRNA LINC00607 mediates angiogenic function January 26, 2023 Frederike Boos
- Genetic Inhibition of Mitochondrial Permeability Transition Pore Exacerbates Ryanodine Receptor 2 Dysfunction in Arrhythmic Disease January 21, 2023 Arpita Deb
- A physiologic increase in brain glucagon action alters the hepatic gluconeogenic glycogenolytic ratio but not glucagon's overall effect on glucose production January 18, 2023 Dale S Edgerton
- Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases December 27, 2022 Wenqiang Song
- Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk December 22, 2022 Dalton L Greenwood
- Activation of basal forebrain-to-lateral habenula circuitry drives reflexive aversion and suppresses feeding behavior December 21, 2022 Jessica L Swanson
- Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation December 13, 2022 Ly Pham
- Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis December 7, 2022 Samantha C Schwager
- Deletion of <em>Jazf1</em> gene causes early growth retardation and insulin resistance in mice November 28, 2022 Hui-Young Lee
- Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice November 9, 2022 Ferrol I Rome
- Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration November 8, 2022 Yong Kyung Kim
- Genomic and Phenotypic Trait Variation of the Opportunistic Human Pathogen Aspergillus flavus and Its Close Relatives November 1, 2022 E Anne Hatmaker
- Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (<em>Rgs2</em>) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice October 19, 2022 McKenzie L Ritter
- Sclerostin ablation prevents aortic valve stenosis in mice October 14, 2022 J Ethan Joll
- Ectonucleoside triphosphate diphosphohydrolase-1 (CD39) impacts TGF-β1 responses: insights into cardiac fibrosis and function following myocardial infarction October 14, 2022 Tatiana Novitskaya