Animal Mouse Physiology Core – Serving Vanderbilt Investigators
Instruments and Equipment
We have several instruments and equipment for self-use:
- Promethion - Body composition
- Metabolic cage rental
- Pair-feeding hoppers
- Temperature regulated housing cabinet
- Telemetry System
- SomnoSuite
- Oroboros O2K
Courses & Education
- Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis (November 7-11, 2022)
- Glucose Clamping the Conscious Mouse: A Laboratory Course Mouse Metabolic Phenotyping Center - Vanderbilt University Nashville, TN (October 17-21, 2022)
- See JoVE Production on the Vanderbilt Clamp
- MMPC Grant Programs
Our Mission
To advance research by providing novel experimental tools to the scientific community for phenotyping genetic mouse models related to diabetes, obesity, and other metabolic diseases.Our Goals
- Broaden the scope of techniques available to investigators
- Standardize key methodologies
- Expedite the completion of research
- Compile a database for mouse models of diabetes
Twitter Feed
Great place to do science! Endorsed by the VMMPC. https://t.co/b7Z8jNAAtX
Attendees are mesmerized by @vumcdiabetes seminar delivered by the dynamic @EMatthewMorris2 of @KUDiabetesInst. https://t.co/hqBcLr5Xrk
This should help with definitions and characterization of mouse models. https://t.co/hfFqhy53Go
Excited to have @sarah_stern of Max Planck Florida Institute for Neuroscience speak at Vanderbilt. Great stuff. Electric! @VCARScience @VUBasicSciences https://t.co/AmCIP7aoqW
Recent Publications
- Dephosphorylation of 4EBP1/2 Induces Prenatal Neural Stem Cell Quiescence February 24, 2023 Laura C Geben
- Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility February 7, 2023 Meng Zou
- Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy February 6, 2023 Felicia Kuperwaser
- The endothelial-enriched lncRNA LINC00607 mediates angiogenic function January 26, 2023 Frederike Boos
- Genetic Inhibition of Mitochondrial Permeability Transition Pore Exacerbates Ryanodine Receptor 2 Dysfunction in Arrhythmic Disease January 21, 2023 Arpita Deb
- Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases December 27, 2022 Wenqiang Song
- Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk December 22, 2022 Dalton L Greenwood
- Activation of basal forebrain-to-lateral habenula circuitry drives reflexive aversion and suppresses feeding behavior December 21, 2022 Jessica L Swanson
- Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization December 16, 2022 Kevin R Bersell
- Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation December 13, 2022 Ly Pham
- Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis December 7, 2022 Samantha C Schwager
- Deletion of <em>Jazf1</em> gene causes early growth retardation and insulin resistance in mice November 28, 2022 Hui-Young Lee
- Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration November 8, 2022 Yong Kyung Kim
- Genomic and Phenotypic Trait Variation of the Opportunistic Human Pathogen Aspergillus flavus and Its Close Relatives November 1, 2022 E Anne Hatmaker
- Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (<em>Rgs2</em>) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice October 19, 2022 McKenzie L Ritter