Animal Mouse Physiology Core – Serving Vanderbilt Investigators
Instruments and Equipment
We have several instruments and equipment for self-use:
- Promethion - Body composition
- Metabolic cage rental
- Pair-feeding hoppers
- Temperature regulated housing cabinet
- Telemetry System
- SomnoSuite
- Oroboros O2K
Courses & Education
- Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis (November 7-11, 2022)
- Glucose Clamping the Conscious Mouse: A Laboratory Course Mouse Metabolic Phenotyping Center - Vanderbilt University Nashville, TN (October 17-21, 2022)
- See JoVE Production on the Vanderbilt Clamp
- MMPC Grant Programs
Our Mission
To advance research by providing novel experimental tools to the scientific community for phenotyping genetic mouse models related to diabetes, obesity, and other metabolic diseases.Our Goals
- Broaden the scope of techniques available to investigators
- Standardize key methodologies
- Expedite the completion of research
- Compile a database for mouse models of diabetes
Twitter Feed
Fascinating study suggests that when a subject loses weight they need to commit to keeping it off. Repercussions of weight regain are bad for health. https://t.co/XWKzSnizuK
On this Veteran's Day the VMMPC expresses its appreciation and admiration for all those who served our country. #RESPECT
Tracers in Metabolic Research. King Henri Brunengraber of @cwru is in the room! Wonderful to learn from King Henri. https://t.co/sPDSrScTgF
Tracers in Metabolic Research. Matt Merritt @metabolicminds1 dazzles audience with the vast application of NMR in tracing metabolic pathways. @VUBasicSciences @vumcdiabetes https://t.co/OSRQlwPojD
Recent Publications
- Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice November 9, 2022 Ferrol I Rome
- Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration November 8, 2022 Yong Kyung Kim
- Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (<em>Rgs2</em>) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice October 19, 2022 McKenzie L Ritter
- Sclerostin ablation prevents aortic valve stenosis in mice October 14, 2022 J Ethan Joll
- Behavioral and brain anatomical analysis of Foxg1 heterozygous mice October 12, 2022 Kirsty R Erickson
- Towards differentiation of brain tumor from radiation necrosis using multi-parametric MRI: Preliminary results at 4.7 T using rodent models October 9, 2022 Sean P Devan
- Impaired Dynamic Sarcoplasmic Reticulum Ca Buffering in Autosomal Dominant CPVT2 September 14, 2022 Matthew J Wleklinski
- Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice September 8, 2022 Sherif Abdelhamed
- Glucagon-like peptide-1 receptor differentially controls mossy cell activity across the dentate gyrus longitudinal axis September 5, 2022 Alex Steiner
- Exon 2-mediated deletion of Trem2 does not worsen metabolic function in diet-induced obese mice August 31, 2022 Nathan C Winn
- High fat diet blunts stress-induced hypophagia and activation of Glp1r dorsal lateral septum neurons in male but not in female mice August 11, 2022 Michelle B Bales
- Parathyroid hormone-related protein in breast cancer bone metastasis August 11, 2022 Rachelle W Johnson
- EGFR-mediated activation of adipose tissue macrophages promotes obesity and insulin resistance August 10, 2022 Shirong Cao
- Neuropeptide Y modulates excitatory synaptic transmission and promotes social behavior in the mouse nucleus accumbens August 2, 2022 Nicholas K Smith
- <em>Helicobacter pylori</em> actively suppresses innate immune nucleic acid receptors July 29, 2022 Samuel D R Dooyema