Animal Mouse Physiology Core – Serving Vanderbilt Investigators
Instruments and Equipment
We have several instruments and equipment for self-use:
- Promethion - Body composition
- Metabolic cage rental
- Pair-feeding hoppers
- Temperature regulated housing cabinet
- Telemetry System
- SomnoSuite
- Oroboros O2K
Courses & Education
- Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis (November 7-11, 2022)
- Glucose Clamping the Conscious Mouse: A Laboratory Course Mouse Metabolic Phenotyping Center - Vanderbilt University Nashville, TN (October 17-21, 2022)
- See JoVE Production on the Vanderbilt Clamp
- MMPC Grant Programs
Our Mission
To advance research by providing novel experimental tools to the scientific community for phenotyping genetic mouse models related to diabetes, obesity, and other metabolic diseases.Our Goals
- Broaden the scope of techniques available to investigators
- Standardize key methodologies
- Expedite the completion of research
- Compile a database for mouse models of diabetes
Twitter Feed
Don't forget - the Isotope Tracers in Metabolic Research course is filling up! Scholarship applications for students/postdocs are due this Friday, Sept. 23rd. More info here: https://t.co/KJMaVH696i https://t.co/AeZ0u9z64j
Congrats to VMMPC alum @AshleySWilliam. Oh and also to her illustrious colleagues @paul_grimsrud and @DebMuoio. https://t.co/2tsJ2bASfg
Gurus of the Mouse Clamp. Thomas Nielsen of Novo Nordisk Foundation Center @Metabolcenter in Copenhagen and @louise_lantier of VMMPC convene in Nashville. https://t.co/SQ11rjR3Xq
Proud to be a part of an innovative and productive DRC under the exceptional leadership of Dr. Al Powers. https://t.co/kjoT8S23u6
Recent Publications
- Glucagon-like peptide-1 receptor differentially controls mossy cell activity across the dentate gyrus longitudinal axis September 5, 2022 Alex Steiner
- Exon 2-mediated deletion of Trem2 does not worsen metabolic function in diet-induced obese mice August 31, 2022 Nathan C Winn
- High fat diet blunts stress-induced hypophagia and activation of Glp1r dorsal lateral septum neurons in male but not in female mice August 11, 2022 Michelle B Bales
- Parathyroid hormone-related protein in breast cancer bone metastasis August 11, 2022 Rachelle W Johnson
- EGFR-mediated activation of adipose tissue macrophages promotes obesity and insulin resistance August 10, 2022 Shirong Cao
- Neuropeptide Y modulates excitatory synaptic transmission and promotes social behavior in the mouse nucleus accumbens August 2, 2022 Nicholas K Smith
- <em>Helicobacter pylori</em> actively suppresses innate immune nucleic acid receptors July 29, 2022 Samuel D R Dooyema
- Podocytes derived from human induced pluripotent stem cells: characterization, comparison, and modeling of diabetic kidney disease July 26, 2022 Julie Bejoy
- DC ENaC-Dependent Inflammasome Activation Contributes to Salt-Sensitive Hypertension July 21, 2022 Ashley Pitzer
- MeCP2 loss-of-function dysregulates microRNAs regionally and disrupts excitatory/inhibitory synaptic transmission balance July 19, 2022 Patricia M Horvath
- Astrocytic GABA transporter 1 deficit in novel SLC6A1 variants mediated epilepsy: Connected from protein destabilization to seizures in mice and humans July 15, 2022 Felicia Mermer
- Rab11FIP1-deficient mice develop spontaneous inflammation and show increased susceptibility to colon damage July 12, 2022 Sudiksha Rathan-Kumar
- Lens Aquaporin-5 Inserts Into Bovine Fiber Cell Plasma Membranes Via Unconventional Protein Secretion July 11, 2022 Romell B Gletten
- An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload July 9, 2022 Magdalene K Ameka
- Human Papillomavirus-Associated Oral Cavity Squamous Cell Carcinoma: An Entity with Distinct Morphologic and Clinical Features July 8, 2022 James S Lewis