Expedited Phenotyping
Mice from these vendors do not require quarantine:
- Jackson Labs
- Harlan Teklad
- Taconic Farms
- Charles River Labs
- National Cancer Institute
- National Institute of Aging
- UC Davis Mouse Biology Program
Courses & Education
- Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis (November 8-12 2021)
- Glucose Clamping the Conscious Mouse: A Laboratory Course Mouse Metabolic Phenotyping Center - Vanderbilt University Nashville, TN (October 18-22, 2021)
- See JoVE Production on the Vanderbilt Clamp
- MMPC Grant Programs
Our Mission
To advance research by providing novel experimental tools to the scientific community for phenotyping genetic mouse models related to diabetes, obesity, and other metabolic diseases.Our Goals
- Broaden the scope of techniques available to investigators
- Standardize key methodologies
- Expedite the completion of research
- Compile a database for mouse models of diabetes
Twitter Feed
Harrison Society researcher discovers key regulator of kidney cell structure https://t.co/Y1qYetWGeS via @vumchealth
GCCM XX coming to a close. Thanks to participants and the staff of @mousecentral. Not shown @mcguinness_owen. Not shown @AJLutkewitte not who was convalescing in hotel after wild celebration of successful procedure. @NationalMMPC @vumcdiabetes @VUBasicSciences @TheBurro34 https://t.co/4KPwwFFMUk
The Burro @TheBurro34 addresses GCCM XX participants on considerations when glucose clamping mice. @NationalMMPC @vumcdiabetes @VUBasicSciences https://t.co/CdkhfsYEsQ
Recent Publications
- Metabolic stress induces GD2(+) cancer stem cell-like phenotype in triple-negative breast cancer November 23, 2021 Appalaraju Jaggupilli
- Peptide-YY(3-36)/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic beta-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries November 15, 2021 Brandon B Boland
- The impact of intermittent exercise on mouse ethanol drinking and abstinence-associated affective behavior and physiology November 13, 2021 Samuel W Centanni
- β-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages November 6, 2021 Cody L Stothers
- mGlu<sub>1</sub> potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits November 3, 2021 James Maksymetz
- Determining the pharmacologic window of bisphosphonates that mitigates severe injury-induced osteoporosis and muscle calcification, while preserving fracture repair November 1, 2021 M Saito
- Endogenous cannabinoids are required for MC4R-mediated control of energy homeostasis October 16, 2021 Yu Yong
- Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity October 14, 2021 Fabian Bock
- Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males October 13, 2021 Emily M Walker
- CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis October 9, 2021 Dina Polosukhina
- Pharmacological blockade of the EP3 prostaglandin E<sub>2</sub> receptor in the setting of type 2 diabetes enhances β-cell proliferation and identity and relieves oxidative damage October 9, 2021 Karin J Bosma
- Therapeutic MK2 inhibition blocks pathological vascular smooth muscle cell phenotype switch October 8, 2021 J William Tierney
- YAC128 mouse model of Huntington disease is protected against subtle chronic manganese (Mn)-induced behavioral and neuropathological changes September 20, 2021 Jordyn M Wilcox
- Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs September 17, 2021 Karrie D Dudek
- Common tumor-suppressive signaling of thyroid hormone receptor beta in breast and thyroid cancer cells September 17, 2021 Eric L Bolf