Animal Mouse Physiology Core – Serving Vanderbilt Investigators
Instruments and Equipment
We have several instruments and equipment for self-use:
- Promethion - Body composition
- Metabolic cage rental
- Pair-feeding hoppers
- Temperature regulated housing cabinet
- Telemetry System
- SomnoSuite
- Oroboros O2K
Courses & Education
- Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis (November 7-11, 2022)
- Glucose Clamping the Conscious Mouse: A Laboratory Course Mouse Metabolic Phenotyping Center - Vanderbilt University Nashville, TN (October 17-21, 2022)
- See JoVE Production on the Vanderbilt Clamp
- MMPC Grant Programs
Our Mission
To advance research by providing novel experimental tools to the scientific community for phenotyping genetic mouse models related to diabetes, obesity, and other metabolic diseases.Our Goals
- Broaden the scope of techniques available to investigators
- Standardize key methodologies
- Expedite the completion of research
- Compile a database for mouse models of diabetes
Recent Publications
- Unbalanced redox status network as an early pathological event in congenital cataracts September 7, 2023 Eloy Bejarano
- Elevated liver glycogenolysis mediates higher blood glucose during acute exercise in Barth syndrome August 31, 2023 George G Schweitzer
- Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2 August 30, 2023 Erick Spears
- Phenotypically sorted highly and weakly migratory triple negative breast cancer cells exhibit migratory and metastatic commensalism August 30, 2023 Lauren A Hapach
- Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity August 22, 2023 Jeeyeon Cha
- A novel role for PGE<sub>2</sub>-EP<sub>4</sub> in the developmental programming of the mouse ductus arteriosus: consequences for vessel maturation and function August 11, 2023 Michael T Yarboro
- Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity August 10, 2023 Ryan P Ceddia
- The MODY-associated TALK-1 L114P mutation causes islet α-cell overactivity and β-cell inactivity resulting in transient neonatal diabetes and glucose dyshomeostasis in adults August 7, 2023 Arya Y Nakhe
- Dopamine release at the time of a predicted aversive outcome causally controls the trajectory and expression of conditioned behavior August 6, 2023 Munir Gunes Kutlu
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia August 3, 2023 Ana Regina Cabrera
- SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells August 3, 2023 Hitoshi Iida
- Regulation of mTOR Signaling: Emerging Role of Cyclic Nucleotide-Dependent Protein Kinases and Implications for Cardiometabolic Disease July 29, 2023 Fubiao Shi
- Formate oxidation in the intestinal mucus layer enhances fitness of <em>Salmonella enterica</em> serovar Typhimurium July 27, 2023 Maria G Winter
- Extracellular matrix remodelling in obesity and metabolic disorders June 29, 2023 Vishal Musale
- Extensive characterization of a Williams syndrome murine model shows Gtf2ird1-mediated rescue of select sensorimotor tasks, but no effect on enhanced social behavior June 28, 2023 Kayla R Nygaard