Cardiovascular Pathophysiology Core

The objective of the Cardiovascular Pathophysiology Core (CPC) is to provide investigators at Vanderbilt and outside institutions a cost-effective means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations. For many studies, multiple measurements can be coordinated with the other Cores of the MMPC: for example, non-invasive serial echocardiographic and blood pressure determinations during a period of high-fat feeding or other environmental stress, measuring the metabolic response to exercise on a subset of mice, and histologic evaluation on sacrifice. The CPC also offers several surgical techniques to induce myocardial injury (infarction, aortic banding, and ischemia/reperfusion injury).

Director: Antonis K. Hatzopoulos, Ph.D.
P425C Medical Research Building IV
Office: (615) 936-5529

 

Staff: Lin Zhong, Ph.D.

Services

Cost for Investigator-initiated research

Cost for Industry-initiated research